![]() ![]() What’s the difference between Toprol XL and Lopressor? However, if you take a combination product that contains metoprolol succinate and a diuretic (water pill) such as hydrochlorothiazide (for example, Dutoprol), it can make you urinate more than usual. No, Toprol XL (metoprolol succinate) does not make you urinate a lot. Weight gain is a possible side effect of beta-blockers, especially older beta-blockers like metoprolol succinate (Toprol XL). Take your medication at around the same time every day to get the best effect and make it easier to remember. If Toprol XL makes you feel dizzy, it may help to take it at bedtime. Take Toprol XL with or immediately after a meal, preferably your morning meal. What is the best time of day to take Toprol XL? ![]() Frequently Asked Questions about Toprol XL (metoprolol succinate) ![]()
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